Engineering Discovery
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Making biological data reusable and cumulative
From fragmented experiments to models of biological systems.
Apr 30
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Smrithi Sunil
3
1
January Roundup
Replication, general managers, bridging biological structure and function, and more.
Feb 2
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Smrithi Sunil
3
Can We Engineer Creativity?
Or, the Boyden Paradox
Jan 10
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Smrithi Sunil
7
1
December Roundup
CWT favorite episodes of 2025, a number of metascience updates, and the possibility of atomic resolution in cells.
Dec 31, 2025
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Smrithi Sunil
1
Inside the movement that’s rewriting how we do science
With new labs, funding models, and institutions, metascience is reinventing the machinery of discovery.
Dec 11, 2025
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Smrithi Sunil
and
Big Think
4
2
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November Roundup
Predictive validity, Beyond the endless frontier, and Brain tissue freezing.
Dec 1, 2025
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Smrithi Sunil
5
Reflections on the PhD Prospectus
More than just a milestone to check off.
Nov 21, 2025
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Smrithi Sunil
6
1
From Blobs to Atoms: The Long Journey of Cryo-Electron Microscopy
How physics, chemistry, and computation came together to bring biology into focus.
Nov 6, 2025
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Smrithi Sunil
5
2
Making the Electron Microscope
In a little over a century, the electron microscope evolved from a tool barely capable of resolving virus particles into one able to capture atomic…
Published on Asimov Press
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Oct 27, 2025
Some ideas to engineer discovery
Notes on research rotations, curiosity vs. platform science, and rethinking the structures around discovery.
Oct 4, 2025
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Smrithi Sunil
16
2
Sawdust and synapses
A brief digression into my woodworking.
Oct 2, 2025
•
Smrithi Sunil
10
5
How do we diagnose Alzheimer’s Disease?
And why an early diagnosis is important, but still lacking.
Sep 25, 2025
•
Smrithi Sunil
4
1
Zooming into biological structure
Building a mosaic of tools to see across spatial scales.
Aug 26, 2025
•
Smrithi Sunil
7
2
Scientific Impact, Seventy Years Later
A historical essay on the life, legacy, and resurgence of Irving Langmuir’s Nobel-winning work.
Jun 1, 2025
•
Smrithi Sunil
1
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Engineering Discovery
I write about science and the process of discovery.
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